Xeno Laboratories HCG 5000 IU Lyophilized Research Vial

Human chorionic gonadotropin is a glycoprotein hormone with an alpha subunit of 92 amino acids and a beta subunit of 145. In the body it is produced by the placenta, and pharmaceutically it is extracted from urine or made recombinantly. Its beta subunit is what makes it different from luteinising hormone, but both bind the same receptor, which is why hCG is used as a surrogate input whenever Leydig cell response is being studied.

Add bacteriostatic water down the wall of the vial and swirl gently instead of shaking, because the hormone is a protein and foaming damages it. The label arithmetic of the approved products is a useful template: 10000 USP units with 10 ml of diluent gives 1000 IU per ml. The mixed solution keeps in a 2 to 8 C refrigerator for 30 to 60 days according to the same labels, while the sealed powder stays stable when kept cold and dry.

Published pharmacokinetics give a two-phase profile: an initial half-life of 6 to 11 hours and a terminal half-life of 23 to 37 hours. After intramuscular injection, one frequently cited study measured about 31 hours with a spread of roughly 3 hours either way. The long terminal phase explains why the substance stays detectable in urine for 7 to 10 days in immunoassays, against a positive threshold of about 5 IU/L.

No. hCG drives the Leydig cells directly, which is why testicular output can rise while it is present, but it does not restore the hypothalamic and pituitary signal that shut down. Reference material is explicit on this point, and a SERM remains the tool associated with restarting the axis. Reading a rise in testosterone during gonadotropin exposure as proof of axis recovery is a known error and the sources warn against it.

The approved labels list contraindications including precocious puberty, androgen-dependent tumours and known allergy to hCG, and they note that raising intratesticular testosterone can increase aromatisation to estradiol, so estrogen-linked effects such as water retention are described. Higher exposure is associated with ovarian hyperstimulation in women and with testicular response in men. This sort of information belongs in a clinical context, and no self-directed use is described here.

This 5000 IU vial is listed as research material with international checkout and a U.S. domestic option. Orders are handled within one to two business days and every batch ships with an HPLC report and a Certificate of Analysis. Stock, variant and the current price are shown in the product block above; at the time of checking, the listing carried an out of stock marker while packs are restocked, so confirm the stock line before ordering.