Isotretinoin - Isotroin 10 mg and 20 mg Capsules for Severe Acne

Isotretinoin - Isotroin 10 mg and 20 mg Capsules

Isotretinoin is a retinoid for severe nodular acne that has not improved with other treatment, including antibiotics such as Doxycycline. It slows production of the substances that drive acne, and a course usually runs four to five months, twice daily with meals. It is supplied as Isotroin 10 mg and 20 mg capsules, 30 per pack, by Cipla. It is the most effective acne treatment available and the most tightly controlled, because of the risk to an unborn baby.

• Two variants: Isotroin 10 mg and Isotroin 20 mg
• 30 capsules per pack
• Retinoid for severe nodular acne
• Not to be used in pregnancy

Variant Comparison

Both variants contain isotretinoin, so the difference is the strength and how the daily dose is built from it.

The dose is set by body weight and by how the skin responds, so the two strengths build the daily total rather than serving different conditions: the 20 mg capsule reaches the target with fewer capsules, and the 10 mg allows a gradual reduction at the end of a course. Take the schedule exactly as prescribed and do not extend the course at home.

How Isotretinoin Works

Isotretinoin is a vitamin A derivative that shrinks the sebaceous glands and reduces the oil and skin-cell shedding that block pores, so acne improves from the inside. The same mechanism explains the dryness of lips, eyes, nose and skin, and it also affects the liver and blood fats, which is why blood tests are checked before and during treatment; high fat levels may need a statin such as Atorlip.

Dosage & Administration

Capsules are swallowed whole with water, twice a day with meals, never chewed, crushed or sucked, and no extra doses if spots flare. Isotretinoin must not be used in anyone pregnant or who may become pregnant: it causes pregnancy loss and birth defects, so pregnancy is ruled out before starting and two forms of contraception are required during treatment and afterwards. Tell your doctor about depression, mental illness or suicide attempts in the family, and about diabetes, asthma, osteoporosis or high triglycerides. Stop and seek help for severe headache, blurred vision, seizures, stomach or chest pain, difficulty swallowing, yellowing of the skin or eyes, dark urine, muscle weakness, ringing in the ears, peeling skin, sores or fever. Liver support such as LIV.52, may be discussed with the prescriber, but it does not replace blood monitoring.

This product may require a prescription in your country. It must not be used in pregnancy. Information provided is for educational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before use.